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The blood system that specifically defends against infection is the:

  1. Circulatory System

  2. Immune System

  3. Endocrine System

  4. Nervous System

The correct answer is: Immune System

The immune system is the correct answer because it is the system that is responsible for defending the body against infection. The circulatory system is responsible for transporting blood and nutrients throughout the body, while the endocrine system regulates hormones and metabolism. The nervous system controls communication and coordination in the body. None of these systems are specifically designed to defend against infection like the immune system is.